Validation

Scientific & Clinical


Khymeia since 1998, pioneer in virtual reality technology applied to the rehabilitation sector, has devoted every resource to the development of its technology accompanied by a severe focus on the testing and clinical validation.

All devices and the related exercises, have been developed together with the most relevant rehabilitation centers. That is the reason why the validity of the systems developed by Khymeia is certified by numerous International scientific publications.

Telemedicine for Facio-Scapulo-Humeral Muscular Dystrophy: A multidisciplinary approach to improve quality of life and reduce hospitalization rate? – Disability and Health Journal

The aim of the study "Telemedicine for Facio-Scapulo-Humeral Muscular Dystrophy: A multidisciplinary approach to improve quality of life and reduce hospitalization rate?" published on Disability and…


Virtual reality rehabilitation in patients with total knee replacement: Preliminary results – Gait and Posture

The paper "Virtual reality rehabilitation in patients with total knee replacement: Preliminary results" published on Gait & Posture aims to evaluate the efficacy of a VR system for the enhancement of…


Effects of planar robotic rehabilitation on muscle synergies of the upper limbs in post-stroke subjects – Gait & Posture

The aim of the publication "Effects of planar robotic rehabilitation on muscle synergies of the upper limbs in post-stroke subjects" published on Gait & Posture is to investigate changes in muscle…


Planar robotic rehabilitation of upper limb in post-stroke subjects: Transfer of training effects to a non-trained 3D functional task – Gait & Posture

The study "Planar robotic rehabilitation of upper limb in post-stroke subjects: Transfer of training effects to a non-trained 3D functional task" published on Gait & Posture applies instrumented…


Neurophysiological assessment for evaluating residual cognition in vegetative and minimally conscious state patients: a pilot study – Functional Neurology

The aim of the publication "Neurophysiological assessment for evaluating residual cognition in vegetative and minimally conscious state patients: a pilot study" on Functional Neurology is to assess…


Virtual Reality to Assess and Treat Lower Extremity Disorders in Post-stroke Patients – Methods of Information in Medicine

The purpose of the paper "Virtual Reality to Assess and Treat Lower Extremity Disorders in Post-stroke Patients" published on Methods of Information in Medicine is to identify the support of a…


Decomposing time series data by a non-negative matrix factorization algorithm with temporally constrained coefficients – IEEE Xplore

In the paper "Decomposing time series data by a non-negative matrix factorization algorithm with temporally constrained coefficients" on IEEE Xplore is tested a modified non-negative matrix…


Virtual reality for stroke rehabilitation 2015 – Cochrane Review

Review of the publication COCHRANE REVIEW of Cochrane Australian group 2011, which performed a meta-analysis of virtual reality in gaming and in medical devices for upper limb stroke, noting the…


Telerehabilitation and recovery of motor function: a systematic review and meta-analysis – SAGE Journals

The paper "Telerehabilitation and recovery of motor function: a systematic review and meta-analysis" on SAGE Journals - Journal of Telemedicine and Telecare has the aim of determine whether…


A Decade of Progress Using Virtual Reality for Poststroke Lower Extremity Rehabilitation: Systematic Review of the Intervention Methods – BioMed Research International

The objective of the paper "A Decade of Progress Using Virtual Reality for Poststroke Lower Extremity Rehabilitation: Systematic Review of the Intervention Methods" published on BioMed Research…


Interventions for improving upper limb function after stroke – Cochrane Review

The Cochrane review "Interventions for improving upper limb function after stroke" examines the effectiveness of rehabilitation interventions including 40 complete reviews.


The application of virtual reality in neuro-rehabilitation: motor re-learning supported by innovative technologies – Medical Rehabilitation

The review paper "The application of virtual reality in neuro-rehabilitation: motor re-learning supported by innovative technologies" on Medical Rehabilitation indicates that innovative technologies,…


Telerehabilitation in Poststroke Anomia – BioMed Research International

The paper on BioMed Research International "Telerehabilitation in Poststroke Anomia" shows how the treatment of naming deficits from remote using telerehabilitation is not inferior with respect to…


Reinforced Feedback in Virtual Environment for Rehabilitation of Upper Extremity Dysfunction after Stroke: Preliminary Data from a Randomized Controlled Trial – BioMed Research International

The publication "Reinforced Feedback in Virtual Environment for Rehabilitation of Upper Extremity Dysfunction after Stroke: Preliminary Data from a Randomized Controlled Trial" on BioMed Research…


Telerehabilitation for stroke patients: an overview of reviews – JACCES

The publication "Telerehabilitation for stroke patients: an overview of reviews" in the Journal of Accessibility and Design for All provides an overview of the reviews of the telefacilities for the…


Rehabilitation of Children with Hemiparesis: A Pilot Study on the Use of Virtual Reality – BioMed Research Institute

The paper  "Rehabilitation of Children with Hemiparesis: A Pilot Study on the Use of Virtual Reality" published on BioMed Research International supports the evidence that VR treatment could be a…


Virtual reality for the rehabilitation of the upper limb motor function after stroke – JNER

The publication on Journal of Neuroengineering and Rehabilitation "Virtual reality for the rehabilitation of the upper limb motor function after stroke: a prospective controlled trial" examines 376…


Muscle synergy patterns as physiological markers of motor cortical damage – PNAS

The publication in PNAS "Muscle synergy patterns as physiological markers of motor cortical damage" uses the VRRS system for the innovative study on muscle synergies during the voluntary execution of…


Virtual reality for stroke rehabilitation 2011 – Cochrane review

The publication COCHRANE REVIEW of Cochrane Australian group performed a meta-analysis of virtual reality for gamin and medical devices for upper limb stroke, noting the ineffectiveness of gaming and…


10 years experience in the application of the Reinforced Feedback in Virtual Environment (RFVE) for neurorehabilitation: Preliminary results from a retrospective analysis in stroke patients – IEEE

The aim of the paper "10 years experience in the application of the Reinforced Feedback in Virtual Environment (RFVE) for neurorehabilitation: Preliminary results from a retrospective analysis in…


Assessment of a virtual teacher feedback for the recovery of the upper limb after stroke – Italian Journal of Physiotherapy

The aim of the paper "Assessment of a virtual teacher feedback for the recovery of the upper limb after stroke" in the Italian Journal of Physiotherapy is to assess if the use of an on-line virtual…


Studio delle correlazioni tra sinergie muscolari, volume della lesione cerebrale e indici funzionali, durante l’interazione con un sistema di realtà virtuale (VRRS-EVO 4®), in pazienti con ictus – Giornale Italiano di Medicina Riabilitativa

The publication in Giornale Italiano di Medicina Riabilitativa "Studio delle correlazioni tra sinergie muscolari, volume della lesione cerebrale e indici funzionali, durante l’interazione con un…


The effectiveness of reinforced feedback in virtual environment in the first 12 months after stroke – Polish Journal of Neurology and Neurosurgery

The paper on Polish Journal of Neurology and Neurosurgery "The effectiveness of reinforced feedback in virtual environment in the first 12 months after stroke" has the purpose to investigate the…


Motor Learning Principles for Rehabilitation: A Pilot Randomized Controlled Study in Poststroke Patients – SAGE Journals

In the publication on SAGE Journals "Motor Learning Principles for Rehabilitation: A Pilot Randomized Controlled Study in Poststroke Patients" the authors compared a motor learning-based approach in…


Stability of muscle synergies for voluntary actions after cortical stroke in humans – PNAS

The paper on PNAS "Stability of muscle synergies for voluntary actions after cortical stroke in humans" tests the hypothesis that motor cortices may function to select and activate fixed muscle…


Exercises for Paretic Upper Limb After Stroke: A Combined Virtual-Reality and Telemedicine Approach – Journal of Rehabilitation Medicine

The paper on Journal of Rehabilitation Medicine "Exercises for Paretic Upper Limb After Stroke: A Combined Virtual-Reality and Telemedicine Approach" explains how telerehabilitation may enables a…


Assessment and Treatment of the Upper Limb by Means of Virtual Reality in PostStroke Patients – IOS Press

The publication on IOS Press "Assessment and Treatment of the Upper Limb by Means of Virtual Reality in PostStroke Patients" shows how the performance of VR exercises by post-stroke patients through…


Satisfaction with care in post-stroke patients undergoing a telerehabilitation programme at home – SAGE Journals

The paper on SAGE Journals - Telemedicine and Telecare "Satisfaction with care in post-stroke patients undergoing a telerehabilitation programme at home" compares the degree of satisfaction of…


Virtual environment vs conventional physical therapy for arm motor rehabilitation after stroke: a RCT study – Europa MedicoPhysica

The paper on Europa MedicoPhysica "Virtual environment vs conventional physical therapy for arm motor rehabilitation after stroke: a RCT study" evaluates the effects of virtual environment with…


Reinforced Feedback in Virtual Environment Facilitates the Arm Motor Recovery in Patients after a Recent Stroke – IEEE

The publication "Reinforced Feedback in Virtual Environment Facilitates the Arm Motor Recovery in Patients after a Recent Stroke" in IEEE - Virtual Rehabilitation evaluates whether motor training in…


Impaired Short-term Motor Learning in Multiple Sclerosis: Evidence From Virtual Reality – Sage Journals

The paper on SAGE Journals "Impaired Short-term Motor Learning in Multiple Sclerosis: Evidence From Virtual Reality" investigates the usefulness of VR in the assessment of short-term motor learning…


Post-stroke arm motor telerehabilitation web-based – IEEE

The paper on IEEE "Post-stroke arm motor telerehabilitation web-based" evaluates the effects of a telerehabilitation program designed for ameliorating motor deficits in post-stroke patients with arm…


Virtual Environment Training Therapy for Arm Motor Rehabilitation – Presence

The paper on Presence "Virtual Environment Training Therapy for Arm Motor Rehabilitation" shows how motor recovery in post-stroke patients may be promoted by the enhanced feedback provided in a…


Virtual Environment Training Improves Motor Performance in Two Patients with Stroke: Case Report – JNPT

The publication on Journal of Neurologic Physical Therapy "Virtual Environment Training Improves Motor Performance in Two Patients with Stroke: Case Report" examines two cases of training of stroke…


Augmented Feedback Presented in a Virtual Environment Accelerates Learning of a Difficult Motor Task – Journal of Motor Behaviour

The publication on Journal of Motor Behaviour "Augmented Feedback Presented in a Virtual Environment Accelerates Learning of a Difficult Motor Task" compares augmented feedback treatments and normal…