The Neurowave system consists of an integrated and transportable device for unconventional uni- and multi-modal sensory stimulation (audio, video, tactile) of the patient and the synchronized acquisition of correlated physiological signals (EEG, EMG, ECG, EOG, pulse oximetry, respiratory rate, videomonitoring, cognitive event-related potentials). Other biophysiological phenomena, such as changes in heart rate or the activation of muscular districts, may also be correlated with emotional/video stimuli that are emotional or with no emotional value. The system allows the planning of sensory stimulation protocols to be carried out within the same day or several days; it allows also the population of a centralized database of the patient’s recovery path. The collected data can help to define more reliable prognostic models than the current ones. The system also allows to practice planned stimulations with therapeutic aims.

The main expected benefits are the definition of reliable prognostic methods for patients with disorders consciousness and with diseases of the central nervous system (for example: hypoxic, hemorrhagic, viral, bacterial and traumatic) and the possibility of continuous monitoring of these patients .

The technology is still in the experimental phase and no results are available on the technical performance, safety and clinical efficacy. The clinical and research activities in which the Neurowave technology can constitute a relevant support are the continuous monitoring of the patient and/or the verification of correlations between sensory stimulation and any changes in the patient’s status.

Bologna, Italy; 2010.